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Dantrolene dosing

Miscellaneous · 20 mg vial (reconstitute with 60 mL sterile water) · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low2.5 mg/kg175 mg
standard2.5 mg/kg175 mg
high10 mg/kg700 mg

MALIGNANT HYPERTHERMIA: 2.5 mg/kg IV bolus, repeat q5 min until symptoms resolve, up to 10 mg/kg total. Continue 1 mg/kg q4-6h for 24-48 hr. Difficult to reconstitute — assign helper.

Renal & hepatic adjustment

No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.

Evidence A · MHAUS guidelines; definitive MH treatment

More miscellaneous

Get the exact dose for your patient

Vigil computes Dantrolene for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.