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Glycopyrrolate dosing

Anticholinergics · 0.2 mg/mL · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.002 mg/kg0.14 mg
standard0.004 mg/kg0.28 mg
high0.006 mg/kg0.42 mg

With neostigmine: 0.2 mg per 1 mg neostigmine

Renal & hepatic adjustment

No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.

Onset, duration & pearls

Onset1-2 min
Duration2-4 hr

Side effects: Tachycardia, Dry mouth, Urinary retention.

  • Does NOT cross BBB — no central effects
  • Preferred anticholinergic with neostigmine

More anticholinergics

Get the exact dose for your patient

Vigil computes Glycopyrrolate for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.