Nitroprusside dosing
Antihypertensives · 50 mg vial (reconstitute) · IV Infusion
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.3 mcg/kg/min/kg | 21 mcg/kg/min |
| standard | 2 mcg/kg/min/kg | 140 mcg/kg/min |
| high | 10 mcg/kg/min/kg | 700 mcg/kg/min |
Start 0.3 mcg/kg/min, titrate. Cyanide toxicity risk at >2 mcg/kg/min for >72 hr or >10 mcg/kg/min. Light-sensitive — wrap tubing. Monitor thiocyanate levels if prolonged use.
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Evidence A · Hypertensive emergency guidelines
More antihypertensives
Get the exact dose for your patient
Vigil computes Nitroprusside for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.