Protamine dosing
Anticoagulants · 10 mg/mL · IV Slow Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.5 mg/kg | 35 mg |
| standard | 1 mg/kg | 70 mg |
| high | 1.5 mg/kg | 105 mg |
1 mg per 100 units heparin given. Give slowly over 10 min, max 50 mg. Risk of anaphylactoid reaction, hypotension, pulmonary HTN. Caution in fish allergy/NPH insulin users.
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Evidence A · Standard heparin reversal, cardiac surgery data
More anticoagulants
Get the exact dose for your patient
Vigil computes Protamine for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.