Aprepitant dosing
Antiemetics · 40 mg capsule · PO
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.5 mg/kg | 35 mg |
| standard | 0.5 mg/kg | 35 mg |
| high | 0.5 mg/kg | 35 mg |
40 mg PO 1-3 hr pre-op. NK-1 receptor antagonist. Most effective for preventing late PONV (24-48 hr). IV formulation (fosaprepitant) 150 mg available.
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Evidence A · Diemunsch PONV trial; consensus PONV guidelines
More antiemetics
Get the exact dose for your patient
Vigil computes Aprepitant for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.