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Promethazine dosing

Antiemetics · 25 mg/mL · IV Slow Push / IM

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.15 mg/kg10.5 mg
standard0.2 mg/kg14 mg
high0.25 mg/kg17.5 mg

Typical: 12.5-25 mg. DILUTE before IV (tissue necrosis risk — ISMP high-alert). Give through large bore IV slowly. Causes sedation. Avoid in children <2 yr.

Renal & hepatic adjustment

No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.

Evidence B · Antiemetic efficacy established; safety concerns well documented

More antiemetics

Get the exact dose for your patient

Vigil computes Promethazine for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.