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Diazepam dosing

Benzos · 5 mg/mL · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.05 mg/kg3.5 mg
standard0.1 mg/kg7 mg
high0.2 mg/kg14 mg

Renal & hepatic adjustment

  • Severe (Child-Pugh C)Long-acting active metabolites (desmethyldiazepam) accumulate in hepatic impairment → prolonged effect. Avoid or markedly reduce; prefer lorazepam.

Source: Stoelting's Pharmacology

Onset, duration & pearls

Onset1-3 min
Duration4-6 hr

Side effects: Respiratory depression, Venous irritation, Prolonged sedation.

  • Active metabolite (desmethyldiazepam) — very long half-life
  • Painful on IV injection

More benzos

Get the exact dose for your patient

Vigil computes Diazepam for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.