Lorazepam dosing
Benzos · 2 mg/mL · IV Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.01 mg/kg | 0.7 mg |
| standard | 0.015 mg/kg | 1.05 mg |
| high | 0.02 mg/kg | 1.4 mg |
Typical: 0.5-2 mg. Longer duration than midazolam (6-8 hr). No active metabolites — preferred in hepatic impairment. Status epilepticus: 0.1 mg/kg (max 4 mg).
Renal & hepatic adjustment
- Severe (Child-Pugh C)Glucuronidation is relatively preserved in liver disease (often the preferred benzo) — still reduce and titrate in severe impairment.
Source: Stoelting's Pharmacology
Evidence A · ESETT trial for status epilepticus; anxiolysis literature
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Get the exact dose for your patient
Vigil computes Lorazepam for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.