Diphenhydramine dosing
Miscellaneous · 50 mg/mL · IV Push / IM
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.25 mg/kg | 17.5 mg |
| standard | 0.5 mg/kg | 35 mg |
| high | 1 mg/kg | 70 mg |
Typical: 25-50 mg IV/IM. Anaphylaxis adjunct: 25-50 mg IV. H1 antihistamine. Causes sedation. Also used for dystonic reactions and pruritus from neuraxial opioids.
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Evidence A · Anaphylaxis adjunct guidelines; pruritus treatment
More miscellaneous
Get the exact dose for your patient
Vigil computes Diphenhydramine for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.