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Vitamin K (Phytonadione) dosing

Miscellaneous · 10 mg/mL · IV Slow Infusion / PO

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.03 mg/kg2.1 mg
standard0.07 mg/kg4.9 mg
high0.14 mg/kg9.8 mg

Warfarin reversal: 2.5-10 mg IV (dilute, infuse over 10-20 min) or PO. IV onset 1-2 hr, full effect 6-12 hr. Anaphylactoid risk with IV. For emergent reversal, combine with PCC/FFP.

Renal & hepatic adjustment

No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.

Evidence A · AHA/ACC anticoagulation reversal guidelines

More miscellaneous

Get the exact dose for your patient

Vigil computes Vitamin K (Phytonadione) for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.