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Ketamine dosing

Induction · 50 mg/mL · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.5 mg/kg35 mg
standard1.5 mg/kg105 mg
high2 mg/kg140 mg

Renal & hepatic adjustment

  • Severe (Child-Pugh C)Hepatic metabolism to norketamine — effect prolonged in severe hepatic impairment; titrate.

Source: Stoelting's Pharmacology

Onset, duration & pearls

Onset60-90 sec IV
Duration10-15 min

Side effects: Emergence delirium, Hypertension, Hypersalivation.

  • Bronchodilator — useful in asthma
  • Co-administer midazolam to reduce emergence reactions

Evidence A · Extensive evidence for induction/analgesia

More induction

Get the exact dose for your patient

Vigil computes Ketamine for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.