Thiopental dosing
Induction · 25 mg/mL · IV Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 3 mg/kg | 210 mg |
| standard | 4 mg/kg | 280 mg |
| high | 5 mg/kg | 350 mg |
Barbiturate induction. Neuroprotective (reduces CMRO2). Contraindicated in porphyria. Causes histamine release and hypotension.
Renal & hepatic adjustment
- Severe (eGFR <30 / dialysis)Reduced protein binding in uremia raises free drug — reduce the dose.
- Severe (Child-Pugh C)Reduced clearance and protein binding increase free drug — reduce the dose.
Source: Stoelting's Pharmacology
Evidence A · Classic induction agent; extensive historical data
More induction
Get the exact dose for your patient
Vigil computes Thiopental for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.