Propofol dosing
Induction · 10 mg/mL · IV Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 1 mg/kg | 70 mg |
| standard | 2 mg/kg | 140 mg |
| high | 2.5 mg/kg | 175 mg |
Renal & hepatic adjustment
- Severe (Child-Pugh C)High, partly extrahepatic clearance — induction dose largely unchanged, but titrate; recovery may be modestly prolonged. Reduce in the elderly/hypovolemic regardless of organ function.
Source: Miller's Anesthesia
Onset, duration & pearls
Onset30-40 sec
Duration5-10 min
Side effects: Hypotension, Apnea, Injection site pain.
- Reduce dose 30-50% in elderly/hypovolemic
- Preferred agent for TIVA
Evidence A · Miller's Anesthesia standard dosing
More induction
Get the exact dose for your patient
Vigil computes Propofol for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.