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Pancuronium dosing

Paralytics · 2 mg/mL · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.06 mg/kg4.2 mg
standard0.1 mg/kg7 mg
high0.12 mg/kg8.4 mg

Long-acting NDMR (60-90 min). Vagolytic — causes tachycardia and hypertension. Renally eliminated. Used in cardiac surgery.

Renal & hepatic adjustment

  • Severe (eGFR <30 / dialysis)Predominantly renal elimination → greatly prolonged block in renal impairment. Avoid; use cisatracurium.
  • Severe (Child-Pugh C)Reduced clearance in hepatic dysfunction prolongs block — prefer cisatracurium.

Source: Stoelting's Pharmacology & Physiology

Evidence A · Well-established long-acting NDMR

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Get the exact dose for your patient

Vigil computes Pancuronium for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.