Rocuronium dosing

Paralytics · 10 mg/mL · IV Push

Calculated, not generated

Weight-based dose

Dose	Per kg	For 70 kg
low	0.6 mg/kg	42 mg
standard	0.9 mg/kg	63 mg
high	1.2 mg/kg	84 mg

RSI dose: 1.2 mg/kg

Renal & hepatic adjustment

Severe (eGFR <30 / dialysis)Intubating dose unchanged, but ~30% renal elimination means a prolonged block in severe renal impairment — monitor TOF and ensure sugammadex is available.
Severe (Child-Pugh C)Hepatic uptake/biliary excretion — onset may be slower and duration prolonged in hepatic dysfunction; titrate to TOF.

Source: Miller's Anesthesia; Stoelting's Pharmacology

Onset, duration & pearls

Onset60-90 sec

Duration30-60 min

Side effects: Tachycardia (mild), Anaphylaxis (rare).

Sugammadex-reversible
RSI dose 1.2 mg/kg gives intubating conditions in ~60 sec

Evidence A · ROCURONIUM trial; sugammadex reversal validated

More paralytics

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Vigil computes Rocuronium for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

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