vigil.aiOpen Vigil →

Lidocaine dosing

Local Anesthetics · 1% (10 mg/mL) · Infiltration / Nerve Block

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low3 mg/kg210 mg
standard4.5 mg/kg315 mg
high7 mg/kg490 mg

Max without epi: 4.5 mg/kg. Max with epi: 7 mg/kg.

Renal & hepatic adjustment

  • Severe (Child-Pugh C)Amide local — hepatic clearance is reduced; lower infusion/maximum dose to avoid systemic toxicity (LAST).

Source: ASRA LAST guidance

Onset, duration & pearls

Onset1-3 min
Duration60-120 min (with epi)

Side effects: CNS toxicity (tinnitus → seizures), Cardiac arrest at high doses.

  • Amide type, also IV antiarrhythmic (1-1.5 mg/kg)
  • IV lidocaine blunts airway reflexes at intubation

Evidence A · Extensively studied local anesthetic

More local anesthetics

Get the exact dose for your patient

Vigil computes Lidocaine for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.