Liposomal Bupivacaine (Exparel) dosing
Local Anesthetics · 13.3 mg/mL · Infiltration / Nerve Block
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 1.3 mg/kg | 91 mg |
| standard | 2 mg/kg | 140 mg |
| high | 2.7 mg/kg | 189 mg |
Max 266 mg (single dose vial). Duration up to 72 hr. Do not admix with bupivacaine (disrupts liposomes). Wait 20 min after lidocaine before injecting.
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Evidence B · FDA approved; variable RCT results for efficacy
More local anesthetics
Get the exact dose for your patient
Vigil computes Liposomal Bupivacaine (Exparel) for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.