Naloxone dosing
Reversal · 0.4 mg/mL · IV Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.001 mg/kg | 0.07 mg |
| standard | 0.004 mg/kg | 0.28 mg |
| high | 0.01 mg/kg | 0.7 mg |
Titrate to effect
Renal & hepatic adjustment
No drug-specific organ adjustment in our database — use clinical judgment and verify against the label.
Onset, duration & pearls
Onset1-2 min
Duration30-45 min
Side effects: Acute withdrawal, Pulmonary edema, Hypertension, Arrhythmias.
- Titrate 40 mcg increments to avoid full reversal
- Re-narcotization risk — monitor closely
More reversal
Get the exact dose for your patient
Vigil computes Naloxone for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.