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Sugammadex dosing

Reversal · 100 mg/mL · IV Push

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low2 mg/kg140 mg
standard4 mg/kg280 mg
high16 mg/kg1120 mg

Immediate reversal: 16 mg/kg

Renal & hepatic adjustment

  • Severe (eGFR <30 / dialysis)Not recommended if CrCl <30 mL/min — the rocuronium–sugammadex complex is renally eliminated and accumulates. If used, monitor for recurarization.

Source: Sugammadex prescribing information; ASA

Onset, duration & pearls

Onset1-3 min
DurationComplete reversal

Side effects: Bradycardia, Anaphylaxis (rare), May reduce OCP efficacy.

  • Binds rocuronium/vecuronium only
  • 16 mg/kg for immediate reversal from deep block

Evidence A · BRIDION trials, rapid reversal validated

More reversal

Get the exact dose for your patient

Vigil computes Sugammadex for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.