Fentanyl dosing
Opioids · 50 mcg/mL · IV Push
Calculated, not generatedWeight-based dose
| Dose | Per kg | For 70 kg |
|---|---|---|
| low | 0.5 mcg/kg | 35 mcg |
| standard | 1 mcg/kg | 70 mcg |
| high | 2 mcg/kg | 140 mcg |
Renal & hepatic adjustment
- Severe (eGFR <30 / dialysis)No active metabolites — a preferred opioid in renal impairment. Still titrate and watch for accumulation with prolonged infusions.
- Severe (Child-Pugh C)Reduced hepatic clearance in severe impairment — reduce/space dosing, especially infusions.
Source: Miller's Anesthesia
Onset, duration & pearls
Onset2-3 min
Duration30-60 min
Side effects: Respiratory depression, Chest wall rigidity, Bradycardia.
- 100x potency of morphine
- Chest wall rigidity risk with rapid bolus >5 mcg/kg
Evidence A · Extensive pharmacokinetic data
More opioids
Get the exact dose for your patient
Vigil computes Fentanyl for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.
Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.