vigil.aiOpen Vigil →

Remifentanil dosing

Opioids · 50 mcg/mL · IV Infusion

Calculated, not generated

Weight-based dose

DosePer kgFor 70 kg
low0.05 mcg/kg/min/kg3.5 mcg/kg/min
standard0.1 mcg/kg/min/kg7 mcg/kg/min
high0.2 mcg/kg/min/kg14 mcg/kg/min

Renal & hepatic adjustment

Metabolized by nonspecific plasma/tissue esterases — organ-independent; no renal or hepatic dose adjustment.

Source: Stoelting's Pharmacology

Onset, duration & pearls

Onset1-2 min
Duration3-5 min

Side effects: Bradycardia, Chest wall rigidity, Opioid-induced hyperalgesia.

  • Context-insensitive half-time ~3 min
  • Plasma esterase metabolism — no organ dependence

More opioids

Get the exact dose for your patient

Vigil computes Remifentanil for your patient's actual weight — and adjusts for renal or hepatic impairment automatically, with the cited rationale. The number is calculated from a verified database, never guessed.

Decision support for licensed clinicians — not a substitute for clinical judgment. Always verify against the package insert and the patient in front of you.